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Senior Scientist I, Chemical Engineering

Company: AbbVie
Location: Crystal Lake
Posted on: October 7, 2019

Job Description:

Process Research and Development invents chemical processes and prepares active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies, and drug product development for AbbVie's pre-clinical and clinical drug pipeline. In addition to working with small molecules, Process R&D also develops antibody drug conjugates (ADC). We create valuable intellectual property through composition of matter, chemical processes, and technologies resulting in cost effective commercial manufacturing processes. We develop the supply chain for APIs and prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content. Chemical Engineers in AbbVie's R&D work in multi-functional teams to develop scalable processes and supply API for safety testing, clinical trials, and formulation development. The teams include Process Chemistry, Pilot Plant Operations, Analytical Chemistry, and Solid State Chemistry. Chemical Engineers support API projects through all phases of development. Early in development, engineers focus on ensuring that the process can be run safely, identifying and addressing major scale-up issues and developing the final (API) process step. Later in the development process, engineers optimize the API process and lead process campaigns run in the R&D Pilot Plant. In the final stage of development, engineers transfer the optimized process to manufacturing and support process validation. Job Description: The successful candidate will play a key role in the Process Chemical Engineering function, specifically the Center for Reaction Engineering, within Process R&D. The core deliverable of the function is to develop robust commercial processes to manufacture small molecule APIs and ADCs. In the Center for Reaction Engineering, the selected candidate will have a strong background in chemical reaction engineering and is expected to address challenging problems with chemical reactions using expertise in chemical kinetics, transport phenomena, mathematical modeling, and reactor design. The candidate is also expected to lead identification and development of novel approaches and technologies to enhance efficiency in process development and commercialization. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects, participate in a cross-functional team of chemists and chemical engineers to deliver specific project needs, and take on a leadership role in developing and implementing solutions. The candidate is required to possess effective oral and written communication skills and be a strong team player. Key Leadership Competencies: Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance. Learns fast, grasps the "essence" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Basic: Bachelors degree in chemical engineering or related scientific field with 10 years of experience OR Masters + 8 years experience OR PhD + 0 years experience Candidates with a PhD in chemical engineering and 2+ years of experience are preferred Candidates are expected to have a strong background in chemical reaction engineering and catalysis and to demonstrate their skills in these fields. Relevant exposure during PhD research would also be counted towards experience.

Keywords: AbbVie, Crystal Lake , Senior Scientist I, Chemical Engineering, Other , Crystal Lake, Illinois

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